May 16, 2008

Yesterday, although the House failed to pass its $162.5 billion fiscal year (FY2008) emergency supplemental appropriations bill, the Senate Appropriations Committee approved its $193 billion version of the FY2008 bill. Whereas the House version of the supplemental neither included science funding nor exceeded the President’s $180 billion request, the Senate bill contains about $10 billion in domestic funding over the President’s request. Of the $10 billion in discretionary funding in its bill, the Senate Appropriations Committee directed $1.2 billion toward its “Science Initiative.” According to the Senate Appropriations Committee’s press release, “to help promote long-term economic development, the Committee is recommending a total of $1.2 billion for programs under the jurisdiction of the National Aeronautics and Space Administration, the National Science Foundation, the National Institutes of Health and the Department of Energy.”

The Senate Appropriations Committee also included $275 million in the supplemental for the Food and Drug Administration (FDA), “including $125 million for food safety activities, and $100 million for medical product and drug safety activities.” According to a press release from Senator Herb Kohl’s (D-WI) Office, the bill would also provide “$40 million… for modernizing FDA science and the FDA workforce; and $10 million… to upgrade FDA facilities and laboratories outside of Washington, DC, which are currently below public safety standards and incapable of performing agency requirements.”

The Senate plans to send the bill to the floor for a vote next week before members leave for their Memorial Day recess on May 26th.

National Institutes of Health (NIH)

The Senate markup of the FY 2008 emergency supplemental appropriations bill includes $400 million for NIH. According to Senator Harkin (D-IA), the Chair of the Senate Labor, Health and Human Services, Education and Related Agencies Appropriations Subcommittee in his May 7th press release, “the $400 million in funding in [the] package would be sufficient to fund approximately 700 additional research grants in FY2008.” FASEB President Robert Palazzo, Ph.D. sent a thank you letter to Harkin for the inclusion of additional funds for NIH in FY2008.

Additionally, Dr. Palazzo sent letters on behalf of FASEB to every member of the Senate Appropriations Committee prior to the May 15th markup, urging them to support the inclusion of funding for NIH in the FY2008 supplemental appropriations bill. Finally, after the Senate Appropriations Committee marked up the bill, Dr. Palazzo sent letters to every member of the Senate to request that they vote for the emergency supplemental bill with NIH funding therein when it makes it to the Senate floor as early as next week.

FASEB has also issued a press release praising the Senate Appropriations Committee for including NIH funding in the supplemental and has sent an alert to its society members, asking them to send letters to their Senators to request their support for funding for NIH and the National Science Foundation in the supplemental appropriations bill on the floor of the Senate next week.

National Science Foundation (NSF)

The FY2008 supplemental appropriations bill provides $200 million each to NSF and to the National Aeronautics and Space Administration, both of which fall under the Senate Commerce, Justice, Science and Related Agencies (CJS) Appropriations Subcommittee. In terms of the money for NSF, the Appropriations Committee allocated $150 million for basic research activities and $50 million for science and math education programs, which include teacher training and graduate fellowships.

In her May 8th press release, Senator Mikulski (D-MD), the Chair of the Senate CJS Appropriations Subcommittee provided, with regard to funding for NSF, that she “understands the importance of investments in basic research and science education… [and that] the $150 million for NSF [would] support approximately 500 additional research grants in the basic sciences.” Senator Mikulski characterized “investments in basic research [as] critically important to the long-term competitiveness of the U.S. economy [inasmuch as they create] new technologies, new industries and higher paying jobs.” She further stated that the $50 million in scholarship funding for NSF “would support approximately 1,650 scholarships and fellowships at the undergraduate and graduate level, in order to educate and energize our future scientists and engineers.”

FASEB has issued a press release praising the Senate Appropriations Committee for including NSF funding in the supplemental and has sent an alert to its society members, asking them to send letters to their Senators to request their support for funding for NIH and NSF in the supplemental appropriations bill on the floor of the Senate next week.

Department of Energy (DOE)

The FY2008 supplemental appropriations bill provides $400 million for DOE though only $100 million of that amount is for DOE’s Office of Science in accordance with the American Competitiveness Initiative; the other $300 million is for environmental management or cleanup. Of the $100 million for DOE’s Office of Science, $50 million is for nuclear fusion, or ITER, which is a joint international research and development project to which the U.S. is a party in France that aims to demonstrate the scientific and technical feasibility of fusion power.

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Farm Bill Passes Without Language Harmful to Animal Research, Creates New Research Institute

 

The advocacy efforts of FASEB and the research community were apparent in the final Farm Bill, which passed both the House and the Senate this week. Legislators removed language eliminating the use of non-purpose bred dogs and cats purchased from Class B dealers, which could have disrupted ongoing research studies, from the final bill. For the past three years, FASEB and its member societies had opposed inclusion of the prohibition, supporting instead a measure in last year’s National Institutes of Health appropriations bill that commissions a study by the National Academies of Science to examine the use of non-purpose bred dogs and cats in research. The conference report of the Farm Bill, in which Congress expands on its intent and motivation for the legislation, directs the United States Department of Agriculture (USDA) to report the results of this study to Congress upon its completion. In a thank you letter to Senator Harkin, who is one of the Farm Bill conference managers, FASEB President Robert Palazzo, Ph.D., affirmed the essential contribution of animals in research and supported the study, stating “we believe it may be appropriate to periodically reassess the scientific need for particular species or to ensure that animal welfare standards are in accordance with the latest scientific understanding about the needs of an animal species.” Many FASEB society scientists took action on this issue, contacting their legislators or sharing stories of their own research programs involving Class B animals, and clearly, it made a difference.  

The final Farm Bill also contained significant changes to the agricultural research programs of the USDA, many of which were in line with FASEB’s initial recommendations for the Farm Bill. The legislation creates a National Institute of Food and Agriculture (NIFA), which would replace the current Cooperative State Research, Education and Extension Service. The head of NIFA will be a “distinguished scientist,” reporting to the USDA Secretary, and NIFA will serve as the home of the competitive extramural research program at USDA, which is now the Agriculture and Food Research Initiative (formerly the National Research Initiative or NRI). The conference report placed a great deal of emphasis on the importance of fundamental research, stating “The Managers intend for NIFA to be an independent, scientific, policy-setting agency for the food and agricultural sciences, which will reinvigorate our nation’s investment in agricultural research, extension, and education… In particular, the Managers intend that the Director place emphasis on fundamental research because this type of research is the engine and cornerstone for all other types of research.” There was also a great deal of language in the bill and conference report that aims to coordinate the extramural and intramural (which the Agricultural Research Service encompasses) research programs of the USDA, another of FASEB’s recommendations. Unfortunately, the bill did not contain any additional money for research, remaining essentially at the previously authorization levels. However, the USDA research programs have never come close to their authorization levels of funding in terms of actual appropriations, so the Farm Bill still leaves plenty of room for growth.  

President Bush has vowed to veto the Farm Bill, primarily because of overall levels of spending in the package. However, the House passed the legislation by a vote of 318-106, and the Senate followed rapidly with a vote of 81-15, both of which are substantially veto-proof margins. The final Farm Bill and conference report, as well as summaries of the various sections, are available here.

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House Holds Hearing on Stem Cell Research

A hearing that the House Committee on Energy and Commerce’s Subcommittee on Health held on “Stem Cell Science: The Foundation for Future Cures,” proved to be popular among members of Congress, with more than a dozen in attendance to hear testimony on the current status of stem cell research. Witnesses included National Institutes of Health (NIH) Director Elias Zerhouni, M.D., embryonic stem cell scientists George Daley, M.D., Ph.D., and John Gearhardt, Ph.D., and adult stem cell researchers and patient advocates. The House held the hearing at the request of Representative Diana DeGette (D-CO), who announced plans to introduce new legislation with Representative Mike Castle (R-DE) that would not only expand the number of human embryonic stem cell (hESC) lines available for federal funding but would also “construct a framework for ethical oversight” for all cell research. A similar DeGette-Castle bill has passed both houses of Congress multiple times but has been unable to garner sufficient votes to override a Presidential veto.

Topics at the hearing ranged from details about the state of the science to current NIH funding levels of stem cell research to the feasibility of NIH serving as a regulatory body to ensure ethical oversight of stem cell research. Comments from the Members present generally fell along partisan lines, with the Democrats on the Subcommittee supporting all types of stem cell research, including embryonic, and the Republican members emphasizing the importance of adult stem cell research and the newer induced pluripotent stem (iPS) cells. Dr. Zerhouni testified that from the scientific standpoint, hESC, adult stem cell, and iPS cell research, are all “faces of the same coin.” In response to questions about the clinical merit of adult versus embryonic stem cells, Zerhouni pointed out that there is an average of 17 years between a basic science idea and clinical trials and that hESC technologies are far younger than their adult stem cell counterparts. He later added, “If we had more resources, we could accelerate the research…” The scientists who testified echoed these points and discussed the current clinical application of adult stem cells.

Although no further details of the upcoming DeGette-Castle legislation were forthcoming, there were a number of questions about the current lack of regulatory framework for ethical oversight of stem cell research. Dr. Zerhouni enthusiastically supported the enactment of “harmonized and cohesive oversight” that would apply to all stem cell research in the U.S., stating “I wish common ground could be found…” and underscored his belief that NIH is the entity best able to administer such a system. Witness statements and a webcast of the hearing are available here.

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Senate Convenes Hearing on Alzheimer’s, Emphasizing Need for Research Funding

The need for research funding at the National Institutes of Health (NIH) and the National Science Foundation (NSF) took center stage at a hearing of the Senate Special Committee on Aging, which focused on Alzheimer’s disease and counted former Speaker of the House Newt Gingrich and former Supreme Court Justice Sandra Day O’Connor among its witnesses. Both Gingrich and O’Connor, who are members of a taskforce of national leaders called the Alzheimer’s Study Group, emphasized multiple times the need for more and better coordination of fundamental and clinical research at NIH. “For every dollar the Federal government now spends through Medicare and Medicaid to care for those with Alzheimer’s,” Gingrich testified, “it invests less than a penny to accelerate the discovery and development of effective therapies through the work of NIH and FDA.” Rudi Tanzi, Ph.D., a neuroscientist and geneticist from Harvard University, underscored the need for research funding, describing his research that NIH has funded on early-onset Alzheimer’s genes.

In response to a question from Senator Ken Salazar (D-CO) regarding current strategies for addressing the disease, Justice O’Connor, who is the caregiver for her husband who suffers from Alzheimer’s, immediately recommended putting more resources into research, particularly translational and clinical research. When Senator Salazar tried to dismiss this as a long-term rather than a short-term solution, Gingrich rebutted him by asserted that we are on the verge of breakthroughs that merit immediate investment. Gingrich also strongly endorsed the role of NSF, stating that Congress should not “underestimate the importance of NSF” in finding a cure for Alzheimer’s. He went on to describe the development of scanning technology and future prospects for nanotechnologies and innovations in the physical sciences that would underlie the biomedical research advances in Alzheimer’s disease. For copies of witness statements and a link to the webcast, please click here.

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GO BACK TO MAY 16, WASHINGTON UPDATE

 

FASEB’s Washington Update is brought to you bi-monthly by the FASEB Office of Public Affairs. We welcome your questions and comments – please contact Carrie Wolinetz at cwolinetz@faseb.org or 301-634-7650. For more information about how to get involved in research advocacy, visit: http://capwiz.com/faseb/home/

 

   
   
 

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